Things that affect permeability

• Low temperature

  • Packed more tightly
  • more rigidity due to less kinetic energy
  • Permeability is reduced as Molecules can‘t move through the membrane
• high temperature

  • more kinetic energy
  • move more freely increasing fluidity
  • diffusion is easier
  • increases permeability
  • however proteins denature
• polar solvent

  • disrupts phospholipid packing
  • increases fluidity
  • more permeable but denatures proteins
• non-polar solvents

  • disrupts fatty acid tail
  • membrane ruptures making it extremely permeable