LFTs

• Which LFT markers are sensitive for hepatocellular injury?

  ALT

  AST
• Which LFT markers may indicate cholestasis?

  ALP

  GGT
• What does bilirubin signify in LFTs?

  Liver's ability to conjugate and excrete bilirubin
• What do albumin and prothrombin time reflect in the liver?

  Synthetic capacity of the liver
• Which conditions are likely to show elevated ALT and AST?

  Viral hepatitis

  Autoimmune hepatitis

  Alcoholic liver disease

  NAFLD

  Drug induced liver injury (paracetamol OD)
• Wich conditions are likely to show elevated ALP and GGT?

  Primary biliary cirrhosis

  Primary sclerosing cholangitis

  Gallstones
• Which conditions may show elevation in ALT, AST (hepatocellular enzymes) and ALP, GGT (cholestatic enzymes)?

  Alcoholic hepatitis

  Metastatic liver disease