Atheroscelrosis Definition

• Atherosclerosis:

  • the most common under-lying cause of all CVD (including myocardial infarction, stroke, peripheral vascular disease and sometimes aortic aneurysms)
  • was described by Thompson 1989 as “A variable combination of changes in the intima consisting of the focal accumulation of lipids, other blood constituents and fibrous tissue, accompanied by changes in the media of the vessel”
  • This definition has been widely adopted & commonly used including by the World Health Organisation