Save
PHAR 541
atypicals
Save
Share
Learn
Content
Leaderboard
Learn
Created by
Moira Lucero
Visit profile
Cards (6)
medically important atypical microorganisms
Chlamydiaceae
Chlamydia
trachomatis
Chlamydophila
pneumoniae
Mycoplasma
Mycoplasma
pneumoniae
Legionella
pneumophila
chlamydia trachomatis
intracellular
microorganism
causes
chlamydia
most common
STD
in US
site of infection
urogenital
(nongonococcal urethritis) --> in some cases can involve cervicitis, endometritis
transmission:
sexual
most pts are asymptomatic
diagnosis: PCR in urine (usually in combination w/ gonorrhea)
chlamydophila pneumoniae
intracellular
microorganism
causes
respiratory
infections (sinusitis, bronchitis, pneumonia) - usually either
asymptomatic
or
mild
resp symptoms
known as an
atypical
microogranism when talking about covering for
respiratory
pathogens (together w/
Mycoplasma
pneumoniae and
Liognella
pneumophila)
diagnosis:
PCR
(resp sample)
mycoplasma pneumoniae
smallest free-living bacteria, pleomorphic
do not have a
cell
wall
--> no gram-stain
diagnosis: PCR
M.
pneumoniae
causes
bronchitis
and
atypical
pneumonia
legionella pneumophila
intracellular
bacteria commonly found in
water
or
moist
environment
multiply in alveolar macrophages, monocytes, and alveolar epithelial cells in humans
transmission:
inhalation
of aerosols
contaminated
water
systems (hot tubs/spas, large plumbing systems, hot water tanks, etc.)
rising incidence but still relatively uncommon
legionella pneumophila (cont.)
causes a mild
respiratory
illness (
Pontiac
fever) or a more
severe
pneumonia (
Legionnaire's
disease)
severe disease usually in elderly, COPD, smokers, immunocompromised pts
diagnosis: urine antigen test --> detects Legionella serogroup 1 - specific LPS