Mutations

Cards (10)

What is a mutation?
A change in the base sequence of DNA that occurs spontaneously
What is substitution?
One base is swapped with another
What is addition?
A base is added in somewhere
What is deletion?
A base is removed from somewhere
What is the result of substitution, deletion and addition?
May cause a different amino acid to be coded for which changes the primary sequence of the protein and its tertiary structure
What increase the chance of mutations?
Carcinogens and radiation
Where do most mutations occur?
In non-coding DNA
What is a mutagenic agent?
Something that speeds up the rate of mutations occuring. Such as UV light and radiation
What is frame shift?
During deletion or addition, bases are shifted which changes the entire sequence after.
What is non-disjunction?
A type of chromosome mutation that occurs in meiosis 1 or 2 that makes the chromosomes not split equally so they can end up in the wrong cells.