Reabsorption location is the proximal tube, with substances transported include Na+, K+, water, and Cl-.
In the descending limb of the loop of Henle, NaCl is transported passively and actively.
In the ascending limb of the loop of Henle, NaCl is transported passively and actively.
In the distal tubule, substances transported include NaCl, H2O, HCO3-, K+, and H+, with some molecules moving from the peritubular capillaries and interstitial fluid into the distal tube of the nephron.
Secretion involves some molecules moving from the peritubular capillaries and interstitial fluid into the distal tube of the nephron, including N-containing waste (ammonia), H+ ions (involved in pH balancing), and some pharmaceuticals.
Control of water balance involves hormone ADH-antidiuretic hormone, made in the hypothalamus and released by the posterior pituitary gland, which acts on the kidneys to maintain water balance.
ADH increases the permeability of the proximal convoluted tube, leading to more water being reabsorbed back into the blood.
Diuretics increase urine production.
Caffeine inhibits Na+ reabsorption, leading to less osmosis and more urine.
Alcohol inhibits ADH, lowering permeability and leading to more water in urine.
Whta does reabsorpition involve: active (requires ATP) and passive transport
Na + is actively pumped (membrane protein)
Cl – moves by passively by electrochemical attraction
Glucose and amino acids (active)
Sets up an osmotic gradient
Hypertonic solution outside the nephron
Water will move out of the nephron passively through membrane proteins called aquaporins
most of the water reabsorption occurs in the proximal convoluted tube
More water is removed in the descending loop of Henle