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core concepts
enzymes
enzymes
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Created by
sophie w
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Cards (23)
what is the definition of enzymes
globular proteins
with a specific
tertiary structure
which act as
biological catalysts
and increase the rate of reaction by lowering the activation energy
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what type of protein are enzymes
globular
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what is meant by metabolism
all
chemical reactions
occurring in the body
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what bonds hold together the tertiary structure of a globular protein such as a enzyme
hydrogen bonds
,
ionic bonds
,
disulphide bridges
and
hydrophobic interactions
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What is an anabolic reaction?
Builds
larger
molecules from smaller molecules
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how do enzymes catalyse reactions
by lowering the
activation energy
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what is a example of an anabolic reaction
condensation
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What is a
catabolic reaction
?
Breaks down larger molecules into smaller molecules
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what is an example of catabolic reaction
hydrolysis
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what is the definition of activation energy
minimum energy required for a
reaction
to occur
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describe the enzymes-substrate complex
this is when a substrate fits into the enzymes
complementary
active site
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what are the two main enzymes action models
lock and key model
and
induced fit model
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describe the lock and key model
The
enzyme
and the
substrate
have specific complementary shapes that fit exactly into one another
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describe the induced fit model
this is when the
substrate
and
active site
are not complementary shapes initially but changes when the substrate bind to the active site
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What factors effect enzyme activity?
inhibitors
,
pH
,
temperature
, substrate concentration and
enzyme concentration
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what are the properties of enzymes
specific shape
,very high
turnover number
and
soluble
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how are enzymes soluble
they have
hydrophilic
r groups
on the outside of the molecule
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what is meant by a high turnover number
this means they can convert
many
molecules of substrate per
unit
time
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how do enzymes have a specific shape
the sequence of
amino acids
determins
their shape
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how do you calculate the rate of reaction from an enzyme graph
draw a tangent at a starting point (such as five
minutes
) and a end point ( such as fifteen minuets) and divide the increase in
mass
by the
time taken
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what i meant by an intracellular enzyme
it is in a solution and
membrane bound
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what is meant by a extracellular enzyme
it will be
secreted
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what will an extreme Change in ph do to the amino acid chains
it may alter the
electrostatic
charge
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