In Asch's research, dissenters (confederates who didn't conform to the majority) were added to the groups, which made participants less likely to conform.
Neto (1995) did a study that proved women are more likely to conform, asserting that individualistic cultures like the US have lower conformity rates compared to collectivist countries.
Lab setting in Asch's research allows for control over extraneous variables and establishes the cause and effect relationship, while real life is more complex and prone to demand characteristics and low external validity.