an illness or disorder of the body or mind that leads to poor health
What are communicable diseases caused by, how do they spread?
pathogens and are transmissible (can be spread between individuals within a population)
Examples of infectious diseases?
Cholera
Malaria
HIV/AIDS
Tuberculosis (TB)
What are the main four types of pathogen?
Bacteria
Viruses
Fungi
Protoctists
Bacteria?
Bacteria are a diverse range of prokaryotic organisms
Some bacteria are non-pathogenic (they do not cause any disease or damage) while others are pathogenic
Pathogenic bacteria do not always infect the hosts of cells, they can remain within body cavities or spaces
What diseases are bacteria responsible for?
Tuberculosis
Ring rot in potato plants
Bacterial meningitis in humans
Tuberculosis- bacteria?
The bacteria infect the lungs, causing a chronic cough and bloody mucus
It is a disease often associated with poor hygiene and sanitation
Bacterial meningitis in humans?
Very few bacteria can cross the barrier created by the meninges (the tissue that surrounds the brain and spinal cord) however N. meningitidis crosses this barrier to cause inflammation
Inflammation of the meninges causes symptoms such as fever, headache, neck stiffness and a characteristic rash
Ring rot - bacteria?
The bacteria infect the vascular tissue and prevent the transport of water, causing the plant to wilt and die
The infection spreads into the potato tubers where the vascular tissue is arranged in a ring, producing the characteristic black ring of rot
Viruses?
Viruses do not have a cellular structure
This means they can't respire, produce ATP, replicate genetic material or synthesise protein
They infect host cells and hijack their machinery to replicate their own genetic material and proteins
What diseases do viruses cause?
HIV/AIDS
Influenza
Tobacco mosaic virus (TMV)
Tobacco mosaic virus (TMV)?
plant virus
The first virus ever discovered was the Tobacco Mosaic Virus (TMV)
TMV infects several plant species
It causes a distinct yellowing of the leaves which produces a mosaic pattern
Influenza - caused by virus pathogen?
3 different influenza viruses infect humans to cause the flu
Influenza A, influenza B and influenza C infect the cells that line the airways
They cause a high temperature, body aches and fatigue
Influenza A is the virus that causes the most cases of flu globally
It has a capsid that surrounds 8 single-stranded molecules of RNA
HIV/AIDS - caused by virus pathogen?
The human immunodeficiency virus (HIV) infects specific cells of the immune system
It is an enveloped retrovirus
The viral enzyme reverse transcriptase produces single-stranded DNA from its viral RNA
DNA polymerase synthesises double-stranded DNA from this single-stranded DNA
The double-stranded DNA is inserted into the host DNA and can remain inactive for many years
Once activated the DNA provirus is used to synthesise new viruses
Protoctista?
Protists are unicellular eukaryotes
What diseases are caused by protoctists?
Potato/tomato late blight
Malaria
Malaria- protoctists?
Plasmodium falciparum is a protist that causes severe forms of malaria in humans
The parasite is spread by mosquitoes
Infected individuals experience fever, chills and fatigue
Potato/Tomato late blight- protoctist?
The pathogen is unusual as it has some fungal characteristics
It is transmitted via spores
The first signs of potato blight are small, dark brown marks on the leaves which quickly increase in size and number
The protist destroys potato and tomato crops leaving them completely inedible
Fungi?
Fungi have a similar structure to plants
Their eukaryotic cells have cell walls and large central vacuoles
However, instead of being made of separate cells, their bodies consist of filaments known as hyphae
These hyphae form a network and spread throughout a host/soil
Fungal diseases are much more common in plants than animals
What are diseases caused by fungi?
Black sigatoka
Ringworm
Athlete's foot
Black sigatoka?
Black Sigatoka is a fungal disease in bananas
It spreads through the leaves of the plant, reducing its ability to photosynthesise
The lack of photosynthesis causes parts of the leaf to die; producing black streaks