The liver structure and function?

• What are the two blood vessels that liver receives from?

  The hepatic portal vein( carries deoxygenated blood from the small intestine) and the hepatic artery( carries oxygenated blood from the heart)
• What does the deoxygenated blood from the small intestines contain?

  nutrients and toxins
• What is the role of the hepatic vein?

  Carries the remaining blood(after processing) to the heart.
• What is a lobule?

  A functional unit that makes up the liver.
• What is the role of kupffer cells and where are they found?

  They are found in the sinusoids of lobules. They are involved in the killing of pathogens
• What is the role of the bile duct?

  To transport bile to the gall bladder for storage until it’s needed for digestion
• What is a canalicus and what is it connected to?

  a space enclosed by hepatocytes. The hepatocytes produce bile which is drained into the canalicus.The canalicus is connected to a bile duct
• What is the purpose of a sinusoid in a lobule?

  The sinusoid allows oxygenated blood from the hepatic artery and deoxygenated blood from the hepatic portal vein to mix together. This increases the oxygen content for the hepatocytes, allowing them to function.
• What is the importance of bile?

  its important in the emulsification of fats
• What is the function of hepatocytes in deamination?

  can remove amine groups from amino acids.NH2 can be converted to ammonia. because ammonia is toxic, it’s then converted to urea. Urea can e removed from the body via the kidneys
• What is the function of hepatocytes in detoxification?

  can detoxify toxins such as alcohols. Ethanol can be converted to fatty acids, which can either be stored or used in respiration
• What is the function of amino acids in regulation of blood glucose levels?

  Insulin binds to the receptors of hepatocytes.This signals for the conversion of glucose to glycogen.Glucagon can bind to the receptors on hepatocytes to signal the conversion of glycagon to glucose.
• What enzyme do hepatocytes contain that is involved in the detoxification of alcohols?

  Alcohol hydrogenase