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Topic 5: Health, Disease and the Development of Medicines
5.2 The Immune System
5.2.1 Primary Defenses
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Primary defenses are physical and chemical barriers that prevent pathogens from entering the
body
How does stomach acid act as a primary defense against pathogens?
Destroys pathogens
Cilia move mucus and trapped pathogens out of the body.
True
Cilia are found on the surface of
mucous membranes
and move mucus and trapped pathogens out of the body.
True
Stomach acid destroys
pathogens
that enter the body through food and drink.
True
What is the role of skin as a primary defense against pathogens?
Waterproof barrier
The skin provides a tough, waterproof layer that pathogens cannot easily
penetrate
What type of tracts do mucous membranes line in the human body?
Respiratory and digestive
What is the primary role of primary defenses in the immune system?
Prevent pathogen entry
What are the two types of barriers that make up primary defenses in the immune system?
Physical and chemical
Cilia move mucus and trapped pathogens out of the body by beating in a coordinated
manner
Steps in the destruction of pathogens by stomach acid
1️⃣ Maintains a low pH
2️⃣ Denatures pathogen proteins
3️⃣ Disrupts cell walls
What are the two types of roles the skin plays in preventing pathogen entry?
Physical and chemical
What process does stomach acid use to destroy pathogens by breaking down their proteins?
Denaturation
What are primary defenses in the immune system designed to do?
Prevent pathogen entry
Mucous membranes trap pathogens in sticky mucus.
True
What do mucous membranes secrete to trap pathogens?
Mucus
Mucous membranes trap pathogens in sticky
mucus
The skin is a tough, waterproof barrier that pathogens cannot easily
penetrate
Match the physical barrier with its description:
Skin ↔️ Tough, waterproof layer
Mucous Membranes ↔️ Traps pathogens in mucus
Stomach Acid ↔️ Destroys pathogens in food
Stomach acid maintains a pH between 1.5 and
3.5
, creating a hostile environment for pathogens.
True