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AQA A-Level Biology
4. Genetic Information, Variation, and Relationships Between Organisms
4.1 DNA, Genes, and Chromosomes
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The sequence of bases along DNA forms the
genetic code
What is a gene?
Segment of DNA
Match the DNA component with its detail:
Deoxyribose Sugar ↔️ Forms the backbone of DNA
Nitrogenous Bases ↔️ A, T, C, G
Phosphate Group ↔️ Links nucleotides
Which sex chromosome determines male characteristics?
Y chromosome
The Y chromosome is responsible for determining male sex
characteristics
Steps in DNA replication
1️⃣ DNA helicase creates a replication fork
2️⃣ DNA polymerase synthesizes new strands
3️⃣ DNA ligase joins Okazaki fragments
Which nitrogenous base pairs with guanine in DNA?
Cytosine
DNA is a single-stranded molecule.
False
In DNA, adenine pairs with
thymine
Arrange the types of chromosomes in order of their function:
1️⃣ Autosomes (numbered chromosomes)
2️⃣ Sex chromosomes (X and Y)
Chromosomes are composed of DNA tightly coiled around proteins called
histones
Match the type of chromosome with its primary function:
Autosomes ↔️ Control non-sex characteristics
Sex chromosomes ↔️ Determine sex
DNA replication is a
semiconservative
DNA ligase joins Okazaki fragments on the lagging strand.
True
The nitrogenous bases in DNA pair through hydrogen
bonds
Match the DNA component with its function:
Deoxyribose Sugar ↔️ Forms the backbone of DNA
Phosphate Group ↔️ Links nucleotides
Nitrogenous Bases ↔️ Encode genetic instructions
DNA stores genetic information through its double helix structure.
True
Hydrogen bonds link complementary base pairs in DNA.
True
Chromosomes are composed of a single, double-stranded DNA molecule tightly
coiled
In humans, females have XX sex chromosomes, while males have
XY
DNA replication is a
semiconservative
process.
Match the process with its location:
Transcription ↔️ Nucleus
Translation ↔️ Cytoplasm
Amino acids are linked during translation to form a protein.
True
tRNA carries specific
amino acids
to the ribosome.
Gene expression begins with the transcription of DNA into
mRNA
Gene regulation determines when and how much of a gene product is made.
True
What is the primary function of DNA?
Genetic instructions
What is a gene?
Segment of DNA
What does DNA stand for?
Deoxyribonucleic acid
Match the nucleotide component with its description:
Sugar ↔️ Deoxyribose
Nitrogenous Base ↔️ A, T, C, G
Phosphate ↔️ Attaches to the sugar
Hydrogen bonds hold DNA strands together.
True
Males have two X chromosomes.
False
Autosomes are directly involved in determining sex.
False
Females typically have two X chromosomes, while males have one X and one
Y
What enzyme creates the replication fork during DNA replication?
DNA helicase
DNA is a double-stranded molecule composed of
nucleotides
A gene contains both
coding
and non-coding regions.
True
What forms the backbone of DNA?
Deoxyribose sugar
What are the four nitrogenous bases found in DNA?
A, T, C, G
Chromosomes ensure efficient storage and transmission of
genetic
information.
True
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