3: DNA replication

• the three dna replication theories are conservative, semi-conservative, and dispersive
• Meselson and Stahl proposed that DNA is a semi-conservative molecule
• the origin of replication for E.coli is called OriC
• bacterial DNA replication is initiated by initiator proteins binding the origin of replication
• DNA helicase unwinds dsDNA by breaking the hydrogen bonds
• single stranded binding proteins bind to and stabilize the DNA during the bacterial DNA replication process
• DNA gyrase cuts, unwinds, and reseals DNA during the bacterial DNA replication process