Reducing addiction : drug therapy

    Cards (7)

    • Drug therapies for reducing addiction:
      • Nicotine addiction: Nicotine replacement therapy, Drug treatments ( varencline & bupropion )
      • Gambling addiction : opioid antagonists, antidepressants
    • Nicotine replacement therapy:
      • Drug therapy for reducing nicotine addiction
      • Gradually releases nicotine into the bloodstream at much lower levels than a cigarette & without the other harmful chemicals
      • Controls cravings & prevents relapse
    • Drug treatments for reducing nicotine addiction:
      • Varenicline & bupropion
      • Nicotine-free pills that reduce a person’s cravings & help with withdrawal symptoms
    • Opioid antagonists for reducing gambling addiction:
      • Bind to opiod receptors in the body, blocking them, this prevents the person experiencing the reward response
      • Opioid receptors are import at for processing dopamine
    • Antidepressants as a drug treatment for gambling addiction:
      • SSRIs
      • There’s evidence to support serotonin dysfunction in pathological gambling
      • Reduce symptoms of depression & anxiety, lessens the urge to gamble
      • Low levels of serotonin have been found in people with impaired impulse control
      • SSRIs increase serotonin which reduces impulsivity
    • Drug therapy for reducing addiction AO3:
      • ✅ Support for effectiveness of NRT - meta-analysis of 150 trials that compared NRT with a placebo found NRT was 70% more effective
      • ❌ Lack of blinding in NRT studies - patients can feel whether they got placebo or nicotine
      • ❌ Negative effects of opioid antagonists - stops brain from releasing dopamine, could cause patients to lose pleasure in other areas
      • ❌ Methodological issues in drug therapies for gambling addiction - small sample size, low number of females, no control groups, fail to acknowledge co-morbidity
    • Drug therapy for reducing addiction AO3:
      • ✅ Support for effectiveness of NRT
      • ❌ Lack of blinding in NRT studies
      • ❌ Negative effects of opioid antagonists
      • Methodological issues in drug therapies for gambling addiction