Week 35 Pathology 2

• What are the 3 layers the eye is made up and what do they consist?

  1.     Outer most layer- Fibrous layer

  consists of:

  -cornea

  -sclera

  2.      Middle layer- Vascular layer

  Consists of:

  -Choroid

  -Ciliary body (ciliary muscle and ciliary processes)

  -Iris

  3.      Inner layer- Retina

  -neural layer = photoreceptors of the eye

  -pigmented layer = attaches to the choroid and supports the photoreceptors in the neural layer
• Choroid

  Layer of blood vessels which provides nourishment to the retina.

  Supplies 85% of the blood supply to the eye.

  Comprised of 4 layers:

  1. Haller’s layer- Large diameter blood vessels

  2. Sattler’s layer- Medium diameter blood vessels

  3. Choriocapillaries- capillaries

  4. Bruch’s membrane
• Retinal Pigment Epithelium (RPE)

  • Single layer

  • Inner surface= surrounds the photoreceptors

  • Outer surface= rests on Bruch’s membrane

  • Subretinal space = space between RPE and sensory retina.

  
• In- Inner limiting membrane

  New- Nerve fibre layer

  Generation- Ganglion cell layer

  It- Inner plexiform layer

  Is- Inner nuclear layer

  Only- Outer plexiform layer

  Optometrists- Outer nuclear layer

  Examining- External limiting membrane

  Patient's- Photoreceptors

  Retinas- RPE

  
• Central retinal artery and vein

  
• Age related macular degeneration (AMD)

  • Leading cause of blindness in elderly population

  • Only seen in individuals >50 years old.
• What are the two types of AMD and how do they occur?

  • Dry AMD- no proper cure
  • Wet AMD- happens instantaneously
  • Both occur because of deposits (Drusen) that accumulate within Bruch’s membrane.