Genetic predisposition (biological)
Family- among the general population there's a 0.11% chance of developing ASD. Among siblings there's a 2.2% chance if your sibling has already been diagnosed with ASD.
Twin studies- Bailey et al found the concordance rate for MZ twins was 60% but the rate was 0% for DZ twins
CHD8 gene- Bernier states that people with this gene have a "strong likelihood" of developing autism
Fragile X- This includes intellectual disabilities, a very long face and protruding ears. Around 60% of those with FXS met the diagnosis criteria of ASD