Quiz 1 Immunology

• List the types of innate immunity?

  skin, mucous membranes,iron-binding proteins, phagocytes and complement
• What is the role of complement?

  opsonisation whatever the antibody is attached to

  Membrane attack complex
• What is humoral immunnity and what are they made from?

  Antibodies made from B cells but need to be turnd on by T helper 2 cells
• IgA?

  found in secretions also a dimer
• IgE?

  defense against parasites
• igG?

  crosses placenta and protects newborn
• What drives cell mediated immunity?

  T helper 1
• How does your body know whether to activate humoral or cell-mediated immunity based on the

  antigen it sees?

  Antigen present cell (APC)
• What is passive immunization?

  I give you antibodies
• What are Live-attenuated vaccine?

  beat the heck out of salmonella
• What is Recombinant vaccines?

  insert genes that code for certain antigens into different organisms. 
• What is Adsorbed vaccines?

  Vaccine mixed with inorganic salt for slower absorption and longer lasting immunity
• What is Conjugate vaccines?

  bind weak antigen with strong antigen as a carrier so that immune system will be stronger to weaker antigen
• What are the three types of Aquired resistance?

  alteration in drug target, production of inactivating enzymes, decreased uptake of antibiotics
• Give example of alteration in drug target?

  square protein changes to circle and antibiotic wont be able to bind
• Explain inactivating of enzymes?

  Bacteria will chop up the antibiotic so that it wont be useful
• Explain decreased uptake of antibiotics?

  cell wall becomes less permeable and make efflux proteins that take the antiobiotic so that it never accumlates in bacteria. Can be result of mutation in chromosomes
• What is intrinsic resistance?

  a predictable form of resistance based on mechanism of antibiotic and characteristics of microorganism
• What is Immune serum globulin or gamma globulin?

  igG antibodies
• What are Hyperimmune globulin?

  igG fractions from human subjects with high titers of antibody to a specific disease