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Biology- A level AQA
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Cholera
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Ephie
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Which bacteria causes cholera?
Vibrio cholerae
What does cholera infect?
The
small intestine
What does cholera affect?
Osmosis
What does the cholera bacteria do?
Releases a
toxin
which binds to the
chloride
protein channels
on the cell surface membrane of the
epithelial cells
in the
small intestine
What happens to the protein channels?
They remain open, causing
chloride ions
to move from the
epithelial cells
into the lumen
What does the movement of chloride ions do to the lumen?
Lowers the
water potential
What happens due to the low water potential of the lumen?
Water moves by
osmosis
from the blood, into the
epithelial cells
and into the lumen
what are the main symptoms of cholera?
Diarrhoea
and
dehydration