4.3.2.1 producing monoclonal antibodies

• How are monoclonal antibodies produced?

  From a single clone of cells
• what are the antibodies in monoclonal antibodies specific to?

  one binding site on one protein antigen and so are able target a specific chemical or specific cells in the body
• how are monoclonal antibodies produced?

  by stimulating mouse lymphocytes to make a particular antibody
• What happens to The lymphocytes when producing monoclonal antibodies?

  They are combined with a particular kind of tumour cell to make a cell called a hybridoma cell
• what can the hybridoma cell do?

  It can both divide and make the antibody
• What happens with the single hybridoma cell during the process of monoclonal antibodies?

  Single hybridoma cells are cloned to produce many identical cells that all produce the same antibody
• what happens after the hybridoma cell is cloned?

  A large amount of the antibody can be collected and purified