Phentolamine

Cards (5)

  • What are the complications of phentolamine?
    Altered HR
    Stroke
    MI
    Severe chest pain
    Loss of consciousness (due to low BP)
  • What is phentolamine?
    Non-selective alpha blocker
  • What is the pharmacology of phentolamine?
    Target: adrenergic alpha receptors
    Activity: Competitive antagonist
  • MOA - phentolamine
    Binds to & inhibits alpha-1 adrenergic receptorsinhibits vasoconstriction that is usually caused by adrenaline binding to alpha-1 receptorsvasodilationdecrease TPRdecrease BP
  • What is the indication of phentolamine?
    Hypertensive episodes