non competitive

• non-competitive inhibitor molecules bind to the enzyme away from its active site.

  the site they bind to is known as the enzymes allosteric site
• causes the active site to change shape so substrate molecules can no longer bind to it
• don't compete with the substrate molecules to bind to the active site because they are a different shape
• increasing the concentration of substrate wont make any difference to the reaction rate - enzyme activity will still be inhibited