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Synthetic routed
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Created by
Georgia Marriott
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Cards (26)
Acid, hydrolysis, reagents and conditions.
Six moles aqueous HCl
,
reflux
,
24 hours
Alkaline,
hydrolysis, reagents and conditions.
Aqueous NaOH
,
100°C
Forming nitriles, reagents and conditions.
Haloalkane, reflux, sodium cyanide , ethanol solvent
Nitriles can be reduced to amines.
Lithium
,
aluminium hydride
(
LiAlH4
) in
dry ether
at
room temperature
Nitrile
, +
4H
=
amine
Alkane to halo alkane
X2
UV
alkene to alkane
H2
,
Ni catalyst
,
150
degrees
Alkene to dihaloalkane
X2
20
degrees
Alkene to alcohol
H3PO4,
300
degrees,
60atm
Alcohol to alkene
conc.
H2SO4
Alcohol to aldehyde/ketone:
H2SO4 K2Cr2O7
Aldehyde/ Keytone to alcohol
NaBH4
water
Alkene to haloalkane
HX
20
degrees
Alcohol to haloalkane
NaX
H2SO4
20
degrees
Haloalkane to alcohol
NaOH warm
Haloalkane to amine
excess
NH3 ethanol
solvent
Haloalkane to nitrile
KCN
ethanol reflux
Nitrile to amine
LiAlH4 dil. Acid
Hydroxynitrile to amine
LiAlH4 dil. Acid
aldehyde/ketone to hydroxynitrile
HCN
Aldehyde to carboxylic acid
K2Cr2O7 H2SO4
Hydroxynitrile to carboxylic acid
dil.
HCl reflux
nitrile to carboxylic acid
dil.
HCl reflux
Carboxylic acid to acyl chloride
SOCl2
Acyl chloride to carboxylic acid
Cold H2O
acyl chloride to amide
NH3
20
degrees
Acyl chloride to ester
alcohol
20
degrees