Synthetic routed

Cards (26)

  • Acid, hydrolysis, reagents and conditions.
    Six moles aqueous HCl, reflux, 24 hours
  • Alkaline, hydrolysis, reagents and conditions.
    Aqueous NaOH, 100°C
  • Forming nitriles, reagents and conditions.
    Haloalkane, reflux, sodium cyanide , ethanol solvent
  • Nitriles can be reduced to amines.
    Lithium, aluminium hydride(LiAlH4) in dry ether at room temperature
    Nitrile, + 4H = amine
  • Alkane to halo alkane
    X2 UV
  • alkene to alkane
    H2, Ni catalyst, 150 degrees
  • Alkene to dihaloalkane
    X2 20 degrees
  • Alkene to alcohol
    H3PO4, 300 degrees, 60atm
  • Alcohol to alkene
    conc. H2SO4
  • Alcohol to aldehyde/ketone: H2SO4 K2Cr2O7
  • Aldehyde/ Keytone to alcohol
    NaBH4 water
  • Alkene to haloalkane
    HX 20 degrees
  • Alcohol to haloalkane
    NaX H2SO4 20 degrees
  • Haloalkane to alcohol
    NaOH warm
  • Haloalkane to amine
    excess NH3 ethanol solvent
  • Haloalkane to nitrile
    KCN ethanol reflux
  • Nitrile to amine
    LiAlH4 dil. Acid
  • Hydroxynitrile to amine
    LiAlH4 dil. Acid
  • aldehyde/ketone to hydroxynitrile
    HCN
  • Aldehyde to carboxylic acid
    K2Cr2O7 H2SO4
  • Hydroxynitrile to carboxylic acid
    dil. HCl reflux
  • nitrile to carboxylic acid
    dil. HCl reflux
  • Carboxylic acid to acyl chloride
    SOCl2
  • Acyl chloride to carboxylic acid
    Cold H2O
  • acyl chloride to amide
    NH3 20 degrees
  • Acyl chloride to ester
    alcohol 20 degrees