pharmacmimetics

• which drug is used as antidote for parasymphatomimetics?


  atropine
• function of barbiturates

  CNS depressant when there is stimulation
• function of PAM?

  cholinesterase reactivator( inhibit the function of permanent anticholinesterase)
• side effect of parasympathomimetics

  DUMBBELS

  
• why we don't use acetylcholine clinically?

  1. react with many receptors
  2. highly susceptible to cholinesterase so it break down fast with minimum affect
• Neostigmine clinical use

  1. myasthenia gravis
  2. post-operative intestinal and urinary retention
  3. antidote for atropine toxicity
• physostigmine clinical use

  1. treatment for glaucoma
  2. antidote for atropine toxicity
• example or irreversible, indirect parasympathomimetics

  1. parathion
  2. echothiopate
• therapeutic dose

  is the safe amount of drug which can be given to an adult animal to have a desired effect.
• effective dose

  therapeutic dose used experimentally to produce the desired effect
• median effective dose

  dose producing the desired therapeutic effect of the tested frug to 50% of the animals used experimentally.
• maintenance dose

  amount of medication administered to maintain a desired level of the medication in the blood
• what is sympathetic NS

  fight or flight