In the original diathesis- stress model diathesis (vulnerability) was entirely genetic, the result of a single schizogene. led to the idea of a biologically based schizotypic personality, one characteristic of which is sensitivity to stress. According to Meehl, if a person does not have the schizogene then no amount of stress would lead to schizophrenia. However, in carriers of the gene, chronic stress through childhood and adolescence, in particular the presence of a schizophrenogenic mother, could result in the development of the disorder.