Coronavirus, Rhinovirus.

• Rhinovirus is part of the Picornavirus family.
• Rhinovirus is lability in pH acid.
• Rhinovirus doesn't grow at superior of 33°.
• Rhinovirus grows in diploid human cells.
• Rhinovirus causes a cytopathic effect.
• Infection with Rhinovirus leads to hyperactivation of CCK and cascade signaling that causes the inflammatory response to virus.
• Rhinovirus is the agent of the common cold.
• Rhinovirus infects the mucosae of the first respiratory paths (nose) and other organs.
• Rhinovirus can colonize the human intestine.
• Diagnosis of Rhinovirus infection is exclusively clinic.
• Coronavirus is in the Nidovirus family.
• Coronavirus is an RNA with positive polarity.
• Coronavirus penetrates the nucleocapsid and fuses the envelope with the plasmatic membrane.
• Coronavirus is translated by the protein-synthesis apparatus of the cell.
• Coronavirus transcribes the whole viral genome into antigenome used for the formation of viral progeny and complete transcription of RNA copies.
• HCoV- 229E and HCoV- OC43 are different only for antigenic characters.
• HCoV- OC43 shows hemoagglutination.
• Coronavirus is transmitted through inhalation.
• Colds are affections of respiratory airways.
• Coronavirus replicates in the mucosae of the respiratory apparatus.
• Reinfection with Coronavirus is possible, providing scarce protection.
• Diagnosis of Coronavirus infection includes antigen specific search and nucleotidic sequence in exudate.
• SARS (severe acute respiratory syndrome) is also called acute respiratory syndrome.
• SARS is characterized by atypical pulmonitis, a severe clinical picture, and interhuman infection.
• SARS- CoV, the virus that gives origin to SARS, multiplies quickly in culture.
• Diagnosis of SARS includes virus search in expectorate and mucus, culture isolation, specific genomic sequences, and search of specific antigens through immunofluorescence or immunoenzymatic techniques.
• MERS (middle east respiratory syndrome) is a serious respiratory disease characterized by fever, cough, respiratory problems, and high mortality.