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Enalapril
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Created by
Jessica Jardine
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Cards (5)
What is enalapril?
ACE inhibitor
What is the pharmacology of enalapril?
Target:
ACE
Activity:
Competitive antagonist
MOA - enalapril
Binds to &
inhibits ACE
->
stops conversion
of
angiotensin I
to
angiotensin II
-> less
angiotensin II
-> less
vasoconstriction
&
salt retention
in
kidneys
-> less
blood volume
&
resistance
->
decrease CO
&
TPR
->
decrease BP
What are the indications of enalapril?
Essential HTN
Heart failure
What are the side effects of enalapril?
Diarrhoea
Hypotension
Vomiting