AUBF Sweat

• Sweat is collected using Pilocarpine Iontophoresis.
• Sweat is tested for the levels of Sodium & Chloride.
• A normal value of Sweat Chloride is less than 50mmol/L.
• Values of Sweat Chloride greater than 60mmol/L are indicative of cystic fibrosis.
• A borderline value for Sweat Chloride is between 50-60mmol/L.
• Sweat is used to diagnose cystic fibrosis.
• Signs and symptoms of cystic fibrosis include bulky offensive greasy stools, noticeably salty sweat, frequent respiratory infections and chronic cough, malnutrition, and male infertility (obstructive azoospermia).
• Methods used to test for cystic fibrosis include the Cotlove chloridometer, microtitration with Mercuric Nitrate, CF Analyzer, and Chloride electrode method.