Major obstacles to learning include limited time due to rapid discharge from care, stress of acute and chronic illness, anxiety, sensory deficits, and low literacy, functional health illiteracy, lack of privacy/social isolation of healthcare environments, situational and personal variations on readiness to learn, motivation and compliance, and learning styles, extent of behavioral changes (in number and complexity) required, lack of support and positive reinforcement from providers and for significant others, complexity, inaccessibility, and fragmentation of the healthcare system.