Multiple sclerosis is a demyelinating disease that affects the myelin sheath.
The myelin sheath conducts fast impulses.
Dendrites are extensions towards the cell body.
Axons are extensions away from the cell body.
The manifestation of multiple sclerosis can include weakness, fatigue, respiratory infection, paresthesia (tingling sensation), dysesthesia (pinprick sensation), and Lhermitte’s Sign (electric/shock like sensation when the head is bent).
The anterior horn of multiple sclerosis is motor.
The posterior horn of multiple sclerosis is sensory.
Exacerbations of multiple sclerosis can be triggered by stress, injury, fatigue, hot tub, dehydration, and heat sensitivity.
Diagnosis of multiple sclerosis can be done through an electroencephalogram, which affects white matter, and a white matter MRI, which is done on the brain’s central portion.
Cerebrovascular accident/stroke is a medical emergency and can lead to permanent disability or death.
The manifestations of viral meningitis include fever, nuchal rigidity, Kernig’s sign, Brudzinski sign, photophobia, and vomiting.
Diagnostic tests for viral meningitis include CT-scan before proceeding to Lumbar puncture to rule out brain herniation and Cerebrospinal Fluid Analysis (CSF) to check for increased WBC and glucose.
Viral meningitis is aseptic and is caused by Nisseria Meningitidis.
Hemorrhagic stroke is caused by ruptured aneurysm, often due to chronic hypertension.
Ischemic stroke is caused by thrombus and emboli, with emboli being mobile and can be fat (fracture), air (fluids), or blood.
The brainstem consists of the Midbrain, Pons which is responsible for respiration, and the Medulla Oblongata which is responsible for sneezing, vomiting, and swallowing.
Normal intracranial pressure (ICP) is 5 to 15 mmHg or 7-15 mmHg.
Craniotomy is a procedure that involves making a hole in the skull.
Left sided damage from arteriovenous malformation will manifest in the right side.
Passive range of motion should be done immediately after hospitalisation (acute phase) in anterior cord syndrome.
Glioblastoma is a tumor in the brain that can be dangerous and fatal.
Botulism can be contracted via contaminated canned goods and its nervous system manifestation occurs between 2 to 4 days.
Wernicke’s aphasia (receptive) is characterized by fluent speech.
Subdural hematoma occurs within 48 hours and is located below the dura mater.
The mnemonic for remembering the spinal cord levels is: Breakfast by 8 (bones – 7), Lunch by 12, Dinner by 5, Snack by 5, Midnight snack by 1.
Arteriovenous malformation can present as spaghetti like or tangled arrays and is characterized by vein and artery connections, with capillaries missing.
Seizures can present as focal (one part of hemisphere) or general (both hemispheres are affected), and can be of the tonic clonic or absence type.
Global aphasia is characterized by mixed aphasia.
Decussation refers to the crossing of pathways.
Spinal cord injury can lead to autonomic dysreflexia, distended bladder, and signs of neurogenic shock.
Propoxyphene is used to decrease the respiratory rate in spinal cord injury.
Guillain-Barre syndrome is a demyelination of the peripheral nervous system (spinal and cranial nerves) and can present as ascending paralysis, motor only affection without sensory loss, Miller-Fisher syndrome, or bulbar paralysis.
Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is a progressive disease that can lead to death in 2 to 6 years.
Hypertension is a contributing factor in arteriovenous malformation.
Spinal cord trauma patients should not be fed for 2 days after the trauma.
Anterior cord syndrome is characterized by hypesthesia, decreased pain, and loss of temperature below the level of the injury.
Broca’s aphasia (expressive) is characterized by non-fluent speech.
Risk of respiratory infection is associated with craniotomy.
Mannitol (Osmotrol) is an osmotic diuretic, and its manifestation includes hypercalcemia, which can be identified as a 3.5 less inverted T-wave.