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Human Phys. Lecture
Exam 2 Material
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When a neuron is sending signals to the cell body of a second neuron, we call this a _ synapse.
Axosomatic
_ must join with synaptotagmin in order to alter SNARE as the trigger for neurotransmitter exocytosis.
Calcium
The _ complex is necessary for exocytosis of neurotransmitters.
SNARE Fusion
Complex
Calcium Synaptogmin
Complex
Receptors that utilize secondary messengers are called _ receptors.
Metabotropic
Synapses from a neuron to a muscle cell are called _ junctions.
Neuromuscular
Receptors that directly open an ion channel are called _ receptors.
Ionotropic
What are the two acetycholine receptors called?
Nicotinic
and
Muscarinic
Which of the following would generate an EPSP?
Ca 2+ entering
the
cell.
Which of the following would generate an IPSP?
K+
leaving the cell
Cl-
entering the cell
T/F: The nicotinic receptor is a metabotropic receptor.
False
T/F: The nicotinic receptor will always generate an EPSP.
True
What enzyme breaks down acetycholine and is located on the membrane of the post-synaptic cell?
Acetycholinesterase
(
Ache
)
Atropine is an acetylcholine _.
Antagonist
Serotonin is derived from what amino acid?
Tryptophan
Dopamine, Norepinephrine, and Epinephrine are derived from what amino acid?
Tyrosine
_ is the enzyme located in the cytoplasm of the terminal bouton that breaks down monoamines.
MAO
(
monoamine oxidase
)
Catechol-o-methyl transferase will break down all of the following except _.
Serotonin
A _ is any enzyme that adds a phosphate group to a molecule.
Kinase
A _ is any enzyme that removes a phosphate group from a molecule.
Phosphatase
Which of the following is NOT a neurotransmitter?
Epinephrine
-> its a
hormone
Which of the following can be either a neurotransmitter or a hormone?
Norepinephrine
In the monoamine mechanism of action, the regulatory subunit prefers to bind to _ when present.
cAMP
The cell bodies of neurons that produce dopamine are found in what segment of the brain?
Mesencephalon
Most of the limbic system is found in what segment of the brain?
Telencephalon
The floor of the diencephalon is called the _.
Hypothalamus
What dangles from the floor of the diencephalon?
Pituitary Gland
what gland is located in the epithalamus?
Pineal Gland
The _ is responsible for the unconscious control of your skeletal muscles. It refines the movement of the muscles.
Cerebellum
A byproduct of producing dopamine is _.
Melanin
T/F: Strattera is a drug used to treat ADD that is commonly abused.
False
T/F: GABA and Glycine both open a Chloride channel and generate an IPSP.
True
Glycine is antagonistic to _.
Ach
__ is the neurotransmitter involved in sensations of pain.
Substance P
__ are the group of neurotransmitters that help with relief of pain and euphoria.
Endogenous Opioids
__ is the gaseous neurotransmitter involved in the Viagra mechanism of action.
Nitric Oxide
Ritalin is a drug used to treat ADD that is commonly abused as it deals with what NT?
Dopamine
T/F: In order to contract a muscle, you need to inhibit the antagonistic muscle at the same time.
True
_ can cause spastic paralysis by disrupting the SNARE complex of inhibitory somatic motor neurons.
Tetanus
A form of synaptic plasticity where a NT acts on the presynaptic cell is known as _ transmission.
Retrograde
T/F: Glutamate is an inhibitory amino acid neurotransmitter that opens a Chloride channel.
False
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