Monoegvirales

Cards (5)

  • includes measles, mumps, rabies, and E.bola
  • has a helical nucleocapsid, -ssRNA monopartite and is enveloped
  • it has a Start-stop-reset mechanism
    the RNA-dependent RNA polymerase will start transcription at the leader sequence and when it reaches the intergenic sequences it will repeatedly transcribe Us to create a poly-A tail. then the RDRP will either continue or will fall off and start again.
  • Transcription attenuation is that more mRNA for 3' genes then there are for the 5' genes = density gradient
  • RNA editing: extra nucleotides are insterted= frameshift mutation, allowing ,RNA or encode three proteins from a single gene