Mitosis & cell cycle

• Prophase

  • Chromosomes replicated in interphase
  • Chromosomes shorten and thicken
  • Nuclear envelope breaks down
  • Centrioles divide and each daughter cell moves to opposite poles of cells to form spindle
• Metaphase

  • Chromosomes move to central region of spindle (equator)
  • Attach to spindles at centromere
• Anaphase

  • Chromosome splits and sister chromatids separate
  • Spindle fibres shorten and pull chromatids to opposite poles
• Telophase

  • New nuclear envelope forms as sister chromatids reach poles
  • Spindle breaks down and disappears
  • Chromosomes uncoil
• Cytokenesis

  Whole cell splits to form 2 identical daughter cells