Phospholipid structure

• The hydrophobic tail groups of phospholipids repel water molecules.
• The hydrophilic head group of phospholipids are negatively charged, so they attract water molecules.
• Phospholipids are amphiphilic, meaning they have both polar (hydrophilic) and nonpolar (hydrophobic) regions.
• Bilayer formation is driven by the hydrophobic effect, where the tails of the phospholipids avoid contact with water.