point 3

•  as a result of their heinous acts, both Macbeth and his wife experience profound mental deterioration as guilt overwhelms them. Through this, Shakespeare portrays guilt as divine retribution for acting on sinful ambition.
• “I am in blood Stepped in so far that, should I wade no more, returning were as tedious as go o’er.”
• “I am in blood Stepped in so far that, should I wade no more, returning were as tedious as go o’er.”

   “blood” is used to symbolise the violent crimes Macbeth has committed in order to become and maintain his position as king, by describing him as submerged in a pool of “blood”, Shakespeare uses this gruesome imagery as a metaphor for Macbeth’s devastating guilt, as he is consumed by his wrongdoings-Macbeth’s mind state is “so far” in decline that he finds it less “tedious” to continue in his vicious endeavours than return to his virtuous character, thus marking his descent into madness.-by positioning this line as a response to supernatural appearances, Shakespeare indicates that Macbeth’s insanity is a punishment by God for his sinful ambitions, echoing Christian beliefs of the Jacobean era
• “Out damned spot!” 
• “Out damned spot!” 

  spot” is a reference to earlier in the play, when she had Duncan’s blood on her hands from framing his guards

  rough Lady Macbeth’s inability to wash it from her hands, Shakespeare uses the motif of blood to symbolise her engulfment by guilt.

  - Moreover, Shakespeare’s use of the word “damned” symbolises her impious nature, as she is stained with “damn[ation]” for her sinful deed, further emphasising the notion of holy retribution.

   Shakespeare positions contemporary audiences to view guilt as a punishment by God for sinful deeds, causing mental decay even amongst the most devilish individuals.