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Topic 18: Organic Chemistry III
18.2 Amino Acids, Proteins, and DNA
18.2.1 Amino Acids
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What two functional groups are present in all amino acids?
Amino and carboxyl
The general structure of an amino acid is represented as R - CH - COOH | NH_{2}</latex>, where
R
represents the variable side chain.
Match the component of an amino acid with its description:
Amino group ↔️ Responsible for basic properties
Carboxylic acid group ↔️ Responsible for acidic properties
R-group ↔️ Determines unique properties
The amino group in an amino acid is derived from
ammonia
.
The carboxylic acid group in an amino acid contains a carbon atom double-bonded to an
oxygen
atom.
What determines the specific properties and characteristics of an amino acid?
R-group
Arrange the following properties based on the R-group of amino acids:
1️⃣ Hydrophobicity
2️⃣ Hydrophilicity
3️⃣ Acidity
4️⃣ Basicity
Each amino acid has a unique R-group that leads to different
properties
.
What is the general structure of an amino acid?
R
−
C
H
(
N
H
2
)
−
C
O
O
H
R - CH(NH_{2}) - COOH
R
−
C
H
(
N
H
2
)
−
COO
H
The amino group in an amino acid is derived from
ammonia
What chemical formula represents the carboxylic acid group in an amino acid?
COOH</latex>
The R-group in an amino acid is the same for all amino acids.
False
What determines the specific properties of an amino acid?
R-group
Match the group with its chemical formula and description:
Amino group ↔️
N
H
2
NH_{2}
N
H
2
||| Provides basic properties
Carboxyl group ↔️
C
O
O
H
COOH
COO
H
||| Provides acidic properties
R-group ↔️
R
R
R
||| Determines specific properties
What property does the amino group contribute to an amino acid?
Basic
What property does the carboxyl group contribute to an amino acid?
Acidic
The R-group is responsible for classifying
amino acids
.
Amino acids are organic compounds containing both an amino group and a carboxylic acid group, and they serve as the building blocks of
proteins
The amino group in an amino acid is derived from
ammonia
and is responsible for its basic properties.
The carboxylic acid group in an amino acid contains a carbon double-bonded to oxygen and single-bonded to a
hydroxyl
What determines the specific properties of an amino acid?
R-group
The general structure of an amino acid is represented as
R
−
C
H
(
N
H
2
)
−
C
O
O
H
R - CH(NH_{2}) - COOH
R
−
C
H
(
N
H
2
)
−
COO
H
, where the R-group determines its unique properties
Match the group with its chemical formula and description:
Amino group ↔️
N
H
2
NH_{2}
N
H
2
: Responsible for basic properties
Carboxyl group ↔️
C
O
O
H
COOH
COO
H
: Responsible for acidic properties
R-group ↔️
R
R
R
: Determines specific amino acid properties
Amino acids can be classified based on the properties of their
R-groups
Nonpolar amino acids have hydrophobic R-groups and tend to
cluster
within proteins.
Amino acids are amphoteric substances because they can act as both
acids
and bases
What type of reaction links amino acids to form peptide bonds?
Condensation
Steps in the formation of a peptide bond
1️⃣ Two amino acids combine
2️⃣ Water molecule is eliminated
3️⃣ Peptide bond forms
The R-group of an amino acid determines its
hydrophobicity
or acidity.
The amino group (
N
H
2
NH_{2}
N
H
2
) of an amino acid is responsible for its basic properties
Polar amino acids can form hydrogen bonds with water and are typically located on the surface of
proteins
.
The solubility of amino acids varies based on the polarity of their
R-groups
.
A peptide bond forms when two amino acids undergo a condensation reaction to eliminate a molecule of
water
When two amino acids are linked by a peptide bond, they form a
dipeptide
.
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