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Topic 6: Immunity, Infection and Forensics
6.1 Pathogens and Disease
6.1.2 Transmission of Pathogens
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What is a pathogen?
Biological agent causing disease
A disease is a specific abnormal condition that affects an organism, impairing its normal
functions
Pathogens cause illness, while
disease
is the illness itself.
What are the two main modes of pathogen transmission?
Direct and indirect
Indirect transmission involves pathogens spreading through an intermediary such as contaminated surfaces, vectors, or airborne
particles
Match the direct transmission method with an example:
Physical contact ↔️ Touching an infected person
Air droplets ↔️ Sneezing
Vertical transmission ↔️ Mother to child
The probability of infection through a fomite is inversely proportional to the
volume
of contact.
What are the primary methods of direct transmission?
Physical contact, air droplets, vertical transmission
Physical contact as a method of direct transmission can lead to skin infections like
ringworm
What does the constant
k
k
k
in the direct transmission infection rate formula represent?
Infectivity
A pathogen is the same as a disease.
False
Vertical transmission is a direct transmission method that occurs from
mother
to child.
Match the indirect transmission method with an example:
Fomites ↔️ Staphylococcus aureus on surfaces
Vectors ↔️ Malaria spread by mosquitoes
Airborne particles ↔️ Tuberculosis spores
What are the three types of indirect transmission?
Fomites, vectors, airborne particles
Pathogens carried by insects or animals from one host to another are spread through
vectors
Pathogens in
airborne
particles can remain suspended in the air for extended periods.
What is the primary carrier of pathogens in vector-borne transmission?
Insects or animals
In vector-borne transmission, the vector acquires the pathogen by feeding on an infected
host
Biological vectors carry pathogens passively on their body surface.
False
Match the term with its description in vector-borne transmission:
Pathogen concentration ↔️
C
C
C
Feeding rate ↔️
F
F
F
Transmission efficiency ↔️
T
T
T
What type of host is a person bitten by a mosquito in vector-borne transmission?
Susceptible host
In vector-borne transmission, the vector bites a susceptible host, transmitting the
pathogen
Mechanical vectors involve pathogens developing within the vector.
False
What does the variable
P
i
P_{i}
P
i
represent in the equation for probability of infection?
Probability of infection
Vector-borne transmission occurs when pathogens spread from an infected host to a susceptible host via
vectors
Airborne transmission involves
pathogens
suspended in the air and inhaled by susceptible individuals.
What is the first step in airborne transmission?
Release of pathogens
Key factors influencing airborne transmission include air currents, pathogen viability, and environmental
conditions
What is a pathogen?
Biological agent causing disease
A disease is an abnormal condition affecting an
organism
.
Match the feature with its description in the context of pathogens and diseases:
Pathogen ↔️ Causative agent
Disease ↔️ Abnormal condition
Pathogens are transmitted through two primary modes: direct and
indirect
What is an example of direct transmission through physical contact?
Touching contaminated surfaces
Indirect transmission involves the spread of pathogens via an
intermediary
.
Match the mode of transmission with its method and example:
Direct Transmission ↔️ Air droplets ||| Influenza
Indirect Transmission ↔️ Vectors ||| Malaria
Direct transmission refers to the spread of pathogens directly from an infected host to a susceptible
individual
What is an example of direct transmission through air droplets?
Influenza
Indirect transmission occurs when pathogens are spread through an
intermediary
What is an example of indirect transmission through fomites?
Influenza on doorknobs
Pathogens carried by insects or animals are spread through
vectors
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