12.5 Drug Therapy

• What is the primary aim of drug therapy for schizophrenia?

  Manage symptoms
• Drug therapy for schizophrenia primarily influences brain neurotransmitters
• Which neurotransmitter do typical antipsychotics primarily target?

  Dopamine
• Typical antipsychotics are effective against negative symptoms of schizophrenia.

  False
• Atypical antipsychotics block both dopamine and serotonin receptors.
• Which symptoms of schizophrenia are addressed by atypical antipsychotics?

  Both positive and negative
• What is a higher risk associated with typical antipsychotics?

  Tardive dyskinesia
• Atypical antipsychotics carry a higher risk of weight gain
• Typical antipsychotics can treat both positive and negative symptoms of schizophrenia.

  False
• Arrange the mechanisms of antipsychotic drugs in order of complexity:

  1️⃣ Typical antipsychotics block dopamine receptors

  2️⃣ Atypical antipsychotics block dopamine and serotonin receptors
• What is the effect of typical antipsychotics on dopamine receptors?

  They block them
• Which neurotransmitters are targeted by atypical antipsychotics?

  Dopamine and serotonin
• Atypical antipsychotics are more effective than typical antipsychotics in treating positive symptoms.
• What is the primary goal of drug therapy for schizophrenia?

  Manage symptoms
• Typical antipsychotics block dopamine receptors and are effective against positive symptoms
• Which neurotransmitter do typical antipsychotics primarily target?

  Dopamine
• Atypical antipsychotics block both dopamine and serotonin receptors.
• Atypical antipsychotics are effective against both positive and negative symptoms
• What is the mechanism of action for typical antipsychotics?

  Block dopamine receptors
• Which symptoms do typical antipsychotics primarily address?

  Positive symptoms
• Examples of typical antipsychotics include Haloperidol and Chlorpromazine
• Haloperidol is a typical antipsychotic used to treat hallucinations and delusions.
• Which negative symptom is Risperidone effective in treating?

  Social withdrawal
• Which neurotransmitter, in addition to dopamine, is targeted by atypical antipsychotics?

  Serotonin
• Risperidone and Olanzapine are examples of atypical antipsychotics
• Match the type of antipsychotic with its mechanism of action:

  Typical antipsychotics ↔️ Block dopamine receptors

  Atypical antipsychotics ↔️ Block dopamine and serotonin receptors
• What neurotransmitters do antipsychotic drugs influence in the brain?

  Dopamine and serotonin
• Typical antipsychotics primarily block dopamine receptors.
• Atypical antipsychotics block both dopamine and serotonin receptors.
• Match the antipsychotic type with its mechanism of action:

  Typical antipsychotics ↔️ Block dopamine receptors

  Atypical antipsychotics ↔️ Block dopamine and serotonin receptors
• Which type of antipsychotics addresses both positive and negative symptoms?

  Atypical antipsychotics
• Typical antipsychotics are effective against positive symptoms like hallucinations.
• Atypical antipsychotics have a higher risk of motor side effects compared to typical antipsychotics.

  False
• What is one limitation of antipsychotic drugs in treating schizophrenia?

  They do not cure it
• Tardive dyskinesia, a motor side effect, is primarily associated with typical antipsychotics.
• Steps to manage tardive dyskinesia in a patient on typical antipsychotics:

  1️⃣ Switch to atypical antipsychotics

  2️⃣ Use anticholinergic medications
• Match the side effect of antipsychotic drugs with its management strategy:

  Weight gain ↔️ Diet and exercise plans

  Sedation ↔️ Dosage timing adjustments

  Sexual dysfunction ↔️ Supportive counseling
• What is the primary goal of drug therapy for schizophrenia?

  Manage symptoms
• Typical antipsychotics are effective against both positive and negative symptoms.

  False
• Which neurotransmitter is blocked by typical antipsychotics to reduce positive symptoms?

  Dopamine