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Rivaroxaban
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Created by
Jessica Jardine
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Cards (5)
What is rivaroxaban?
DOAC
(
anticoagulant
)
What is the pharmacology of rivaroxaban?
Target:
Factor Xa
Activity:
Competitive antagonist
What are the indications of rivaroxaban?
Treatment
&
prophylaxis
of
DVT
/
PE
What are the side effects of rivaroxaban?
Diarrhoea
Nausea
Haemorrhage
MOA - rivaroxaban
Competitively
inhibits Factor Xa
->
no activation
of
prothrombin
(
Factor II
) to
thrombin
(
Factor IIa
) ->
no activation
of
fibrinogen
to fibrin ->
no fibrin clot formation
