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Inheritance
inherited disords
cystic fibrosis
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Created by
sophie o
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Cards (16)
What are alleles?
Different versions of a
gene
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What is the difference between dominant and recessive alleles?
Dominant alleles are
expressed
with one copy
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What is the symbol for the dominant allele for normal cell membrane function?
Capital C
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What is the symbol for the recessive allele for defective cell membranes?
Lowercase c
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How many copies of the defective allele must a person inherit to have cystic fibrosis?
Two copies
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What do we call a person with one defective allele and one normal allele?
Carrier
of the
cystic fibrosis
allele
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What is the genotype of a man who is a carrier of the cystic fibrosis allele?
Heterozygous
(
C/c
)
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What is the genotype of a woman who is homozygous for the normal allele?
Homozygous (
C/C
)
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What is the first step in constructing a Punnett square?
Write down the
genotypes
of the
gametes
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What percentage of offspring will be carriers when a heterozygous man and a homozygous normal woman have children?
50%
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What is the genotype of the offspring that do not have cystic fibrosis but are carriers?
Capital C
lowercase c
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What is the ratio of carriers to non-carriers in the offspring from the cross of a heterozygous man and a homozygous normal woman?
1:1
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What is the probability that all offspring could be carriers or all could be unaffected?
These are just
probabilities
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What is the expected outcome ratio when two carriers of the cystic fibrosis allele have children?
1:2:1 ratio
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What percentage of offspring from two carriers will have cystic fibrosis?
25%
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What is the ratio of offspring that are homozygous for the normal allele when two carriers have children?
1 out of 4
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