Anaphylactic shock

• 3 defining characters are

  • acute onset of symptoms (2-30 min)
  • presence of at least 2 symptoms: respiratory compromise, < BP, GI distress, skin irritation
  • cardiovascular compromise from minutes to hours after exposure
• Manifests

  • HA, N, V, acute abd pain, impending doom, erythema, flushing of skin, dyspnea
  • if severe: rapid onset of HPN, neurologic compromise, respiratory distress, cardiac arrest
• 2 body systems are typically involved
• Allergen -> vasodilation -> fluid leaks -> swelling on periphery