intro 2 micropara

• Hooke 1665

  • First observation of cells through corks
• Leeuwenhoek (1673)


  First observation of microorganism
• Carolus Linnaeus introduced binomial nomenclature in 1735
• Binomial nomenclature consists of the genus name followed by the scientific name
• Jenner (1796)


  1st vaccine
• Bassi (1836)

  silkworm fungus
• Semmelweis (1840)


  childbirth fever
• DeBary (1853)


  Fungal plant disease
• Pasteur (1861)


  Disproved spon gen.
• Pasteur 1864


  Pasteurization
• Lister (1867)


  Aseptic Pasteurization
• Koch (1876)

  Germ theory of disease
• Neisser (1879)

  Neisseria Gonorrhoeae
• Koch (1882)


  Pure culture
• Finley (1881)


  Yellow fever
• Koch (1882)

  Mycobacterium tuberculosis
• Hess (1882)


  Agar (solid) media
• Koch (1883)


  Vibrio cholerae
• Metchinikoff (1884)


  Phagocytosis
• Gram (1884)

  Gram-staining procedure
• Escherich (1884)


  Escherich coli (E.coli)
• Pasteur (1857)


  Fermentation
• Petri (1887)


  Petri Dish
• Kitasato (1889)


  Clostridium tetani
• von Bering (1890)


  Diphtheria antitoxin
• Ehrlich (1890)


  Theory of immunity
• Winogradsky (1893)


  Sulfur cycle
• Shiga (1898)

  Shigella dysenteriae
• Chagas (1910)


  Trypanosoma cruzi
• Ehrlich (1910)


  Syphilis
• Fleming, Chain, Florey (1928)


  Penicillin
• Griffith (1928) 


  Transformation in bacteria
• Lancerfield (1834)


  Streptococcal antigens
• Stanley, Nothrop, Summer (1935)


  Crystallized virus
• Beadle and Tatum 


  Relationship between genes and enzyme
• Delbruck and Luria (1943)


  Viral infection of bacteria
• Avery, MacLeod, McMarty (1944)


  Genetic material is DNA
• Lederberg and Tatum (1946)


  Bacterial conjugation
• Watson and Crick (1953)


  DNA structure
• Jacob and Monod (1957)

  Protein synthesis regulation