Fatty, protective sheath that surrounds and insulates the axon in the brain and spinal cord; promotes rapid transmission of nerve impulses
Relapsing-Remitting
Fluctuating course of relapses with associated neurological deficits, followed by periods of partial or total recovery after relapse
Secondary Progressive
Cessation of fluctuations with slow deterioration and progression
Primary Progressive
Deterioration from the beginning
Optic Neuritis
Inflammation of optic nerve
Nystagmus
A vision condition in which the eyes make repetitive, uncontrolled movements
Dysphagia
Difficulty swallowing
Dysarthria
Difficult or unclear articulation of speech
Dysphonia
Difficulty in speaking due to a physical disorder of the tongue, mouth, throat, or vocal cords
Neurodegenerative
Nerve cells in the brain or peripheral nervous system lose function over time and ultimately die
Neuromuscular
The combination of the nervous system and muscles, working together to permit movement
Parkinson’s Disease
Affects the dopamine producing neurons in the midbrain called Substantia Nigra
Huntington’s Disease
Neurons in the basal ganglia degenerate
Amyotrophic Lateral Sclerosis (ALS)
Gradual degeneration of motor neurons
Myasthenia Gravis (MG)
Chronic autoimmune neuromuscular condition
Akinesia
Inability to perform a clinically perceivable movement
Tremor
An involuntary quivering movement
Rigidity
Stiff or inflexible muscles
Postural disturbance
The inability to maintain equilibrium under dynamic and static conditions such as preparation of movements, perturbations, and quiet stance
Basal ganglia
Controls body’s voluntary movements
Hypophonia
Soft speech resulting from lack of coordination in the vocal musculature
Micrographia
Abnormally small, cramped handwriting
Dopamine
Controls memory, mood, sleep, learning, concentration, movement, and other body functions
Bradykinesia
Slowness of movement or speed (or progressive hesitations/halts) as movements are continued
Deep brain stimulation
Surgical procedure that implants a neurostimulator and electrodes which sends electrical impulses to specified targets in the brain responsible for movement control
Psychotropic medication
A group of drugs that doctors may prescribe to treat a variety of conditions
Dementia
Impaired ability to remember, think, or make decisions that interfere with doing everyday activities
Lewy Body dementia
A disease associated with abnormal deposits of a protein called alpha-synuclein in the brain
Vascular dementia
Changes to memory, thinking, and behavior resulting from conditions that affect the blood vessels in the brain
Fronto-temporal dementia
The result of damage to the neurons in the frontal and temporal lobes of the brain
Early onset dementia
An uncommon form of dementia that affects people younger than age 65
Autoimmune condition
A disease in which the body’s immune system attacks healthy cells
Diplopia
Double vision
Ptosis
Drooping of the upper eyelid
Poliomyelitis
A disabling and life-threatening disease caused by the poliovirus
Gullain-Barré Syndrome
A condition in which the immune system attacks the nerve
Lyme Disease
The most common vector-borne disease in the US caused by the bacterium Borrelia burgdorfer
Bell’s Palsy
An unexplained episode of facial muscle weakness or paralysis
Central sleep apnea
Characterized by a lack of drive to breathe during sleep, resulting in repetitive periods of insufficient ventilation and compromised gasexchange