- pituitary gland produces FSH which causes the egg to mature in the follicle, in the ovary
- as egg develops inside follicle, the follicle produces hormone oestrogen
- oestrogen repairs and grows uterus lining, and inhibits (stops) FSH
- When oestrogen rises to high enough level it causes a surge in LH from the pituitary gland, which causes ovulation, and an egg is released from the follicle (day 14 of cycle)
- the follicle then becomes the corpus luteum, and produces oestrogen and progesterone, which both inhibit FSH and LH production from the pituitary, example of negative feedback
- progesterone then maintains uterus lining
- if egg is not then fertilized, then the corpus luteum dies and progesterone levels drop, which causes maintenance of uterus lining to break down, this is called a period