Types of Cell Junctions

Cards (10)

  • Desmosomes:
    • Similar in structure to adherence junctions
    • Intermediate filaments extend into the cytosol of each cell
    • Provide stability to tissues
    • Abundantly found in the epidermis of the skin and between muscle cells of the heart
  • Hemi-Desmosomes:
    • Provide strong attachments between cells and other extracellular materials like the basement membrane of epithelial tissues
    • Most abundant in tissues subjected to constant frictional or abrasive forces
  • Gap Junctions:
    • Open communication channels
    • Transmembrane proteins called connexins join to create tiny tunnels forming gaps between adjacent membranes
    • Allow ions and small molecules to pass freely from one cell to another
    • Allow rapid passage of electrical impulses between cells
    • Particularly abundant in some types of muscle tissue
  • Cells of many tissues are joined together by intercellular junctions located between adjacent cells
  • Types of intercellular junctions:
    • Tight junctions
    • Adherence junctions
    • Desmosomes
    • Hemidesmosomes
    • Gap junctions
  • Tight junctions:
    • Found in tissues lining the surface of organs and body cavities like the stomach, intestines, and urinary bladder
    • Fuse the plasma membranes of adjacent cells together to restrict the movement of substances like hydrochloric acid
  • Adherence junctions:
    • Created when transmembrane proteins anchored to a dense plaque of proteins inside the cell connect the adjacent cell membranes together
    • Microfilaments extend from the plaque into the cytosol of each cell to help resist separation of epithelial tissues
  • Desmosomes:
    • Provide strong adhesion between cells
    • Common in tissues like epithelium and some types of muscular and nervous tissue
  • Hemidesmosomes:
    • Half desmosomes that anchor cells to the basement membrane
    • Help in maintaining the structural integrity of tissues
  • Gap junctions:
    • Areas where the plasma membranes of adjacent cells are fused together
    • Allow for communication and passage of small molecules between cells