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CMB: An Introduction
Types of Cell Junctions
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Fuentes, Joana
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Cards (10)
Desmosomes
:
Similar in
structure
to
adherence junctions
Intermediate filaments
extend into the
cytosol
of each
cell
Provide
stability
to
tissues
Abundantly found in the
epidermis
of the
skin
and between
muscle cells
of the
heart
Hemi-Desmosomes
:
Provide strong attachments between cells and other extracellular materials like the
basement membrane
of
epithelial tissues
Most
abundant
in tissues subjected to
constant frictional
or
abrasive
forces
Gap Junctions
:
Open
communication
channels
Transmembrane proteins called
connexins
join to create tiny
tunnels
forming
gaps
between adjacent membranes
Allow ions and
small
molecules to pass
freely
from one cell to another
Allow rapid passage of
electrical impulses
between cells
Particularly
abundant
in some types of
muscle
tissue
Cells of many tissues are joined together by
intercellular junctions
located between
adjacent
cells
Types of intercellular junctions:
Tight junctions
Adherence junctions
Desmosomes
Hemidesmosomes
Gap junctions
Tight junctions
:
Found in
tissues
lining the surface of
organs
and
body cavities
like the
stomach
,
intestines
, and
urinary bladder
Fuse the
plasma membranes
of adjacent cells together to
restrict
the
movement
of substances like
hydrochloric acid
Adherence junctions
:
Created when
transmembrane proteins
anchored to a dense plaque of
proteins
inside the
cell
connect the adjacent
cell membranes
together
Microfilaments
extend from the plaque into the
cytosol
of each
cell
to help resist
separation
of
epithelial
tissues
Desmosomes
:
Provide strong
adhesion
between
cells
Common in
tissues
like
epithelium
and some types of
muscular
and
nervous
tissue
Hemidesmosomes:
Half desmosomes
that anchor cells to the
basement membrane
Help in maintaining the
structural integrity
of tissues
Gap junctions
:
Areas where the
plasma membranes
of adjacent cells are fused together
Allow for
communication
and
passage
of small molecules between
cells