MYCOVIRO PPT 17-19

• Adenoviridae


  ADENOVIRUSES FAMILY
• Mastadenovirus


  ADENOVIRUSES Genus
• Adenovirus


  dsDNA; naked icosahedral, w/ approximately 50 serotypes
• fecal-oral, respiratory, and direct contact (eye)

  ADENOVIRUSES MOT
• oropharynx

  ADENOVIRUSES Site of Latency
• Adenovirus


  First isolated from adenoid tissue
• Adenovirus


  Causes respiratory disease, eye infections, and GI disease
• Adenovirus


  Epidemic keratoconjunctivitis ("swimming pool

  conjunctivitis")
• Adenovirus


  Can cause cancer in animals
• 1. acute hemorrhagic cystitis

  2. pharyngoconjunctival fever

  3. fatal acute respiratory disease (ARD) - serotype 14

  (rare)

  3 Epidemic keratoconjunctivitis ("swimming pool

  conjunctivitis")
• Adenovirus


  the only virus with a fiber which they use as an
• humans

  Adenovirus: fiber is toxic to
• Adenovirus


  quite stable and can be isolated in human embryonic kidney, and many continuous epithelial cell lines
• Adenovirus


  They are grown in __________ and produce a characteristic Hep-2 cells CPE
• fiber


  use as an organ of attachment and is a hemagglutinin
• 1. Vaccine

  2. Adequate chlorination of swimming pools

  Adenovirus TREATMENT AND PREVENTION
• Astroviridae

  ASTROVIRUSES family
• Mammoastrovirus

  ASTROVIRUSES Genus
• ssRNA viruses

  ASTROVIRUSES Genome
• naked icosahedral

  ASTROVIRUSES Capsid morphology
• Astrovirus


  can cause mild to severe gastroenteritis, especially in infants and children
• Astrovirus


  transmitted through the fecal-oral route (contaminated food or water)
• Stool

  Astrovirus: For diagnosis, what samples are analyzed
• Astrovirus


  These viruses are fastidious
• Astrovirus


  Treatment involves supportive rehydration and

  electrolyte replacement if needed
• Reoviridae


  ROTAVIRUS family
• Rotavirus

  ROTAVIRUS genus
• dsRNA


  ROTAVIRUS genome
• fecal-oral

  ROTAVIRUS mot
• naked icosahedral

  ROTAVIRUS Capsid Morphology
• ROTA


  Latin word for wheel
• Rotavirus


  double- shelled capsule that resembles a wheel or wheels with spokes appearance or wheels with spokes
• Rotaviruses


  most common cause of viral gastroenteritis in infants and children
• Rotavirus

  Most outbreaks occur in the cold months in the temperate zones and year-round in subtropical and tropical regions
• Rotavirus


  Symptoms generally occur suddenly (after 1-4 days incubation) and include vomiting, diarrhea, fever, and, in many cases, abdominal pain and respiratory symptoms
• Rotavirus

  replicates in the epithelial cells in the tips of the microvilli of the small intestine
• Rotavirus

  Not isolated in lab
• ELISA and latex agglutination tests

  Rotavirus laboratory methods
• ELISA and latex agglutination tests


  detect the viral antigens in fecal material
• Rotavirus


  Electron microscopy examination of stool samples can be used