Cohort– study of 2 or more groups of individuals without the disease and differ in one main factor to see who develops particular disease over period of time
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Gather data regarding sequence of events; can assess causality
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Examine multiple outcomes for a given exposure
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Good for investigating rare exposures
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Can calculate rates of disease in exposed and unexposed individuals over time (e.g. incidence, relative risk)
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Large numbers of subjects are required to study rare exposures