Hormonal cascade during puberty
1. Hypothalamus releases gonadotropin-releasing hormone (GnRH), which tells the anterior pituitary to secrete follicle-stimulating hormone and luteinizing hormone
2. In females, LH leads to the release of estrogen in the follicles, whereas in males, it spurs the Leydig cells to release testosterone
3. FSH triggers the sertoli cells to release androgen-binding protein (ABP), which binds to testosterone, creating large local concentrations that trigger sperm production