Pharmacology

    Cards (18)

    • ADRENALINE 1 in 1000 INDICATIONS?
      Anaphylaxis
      Life threatening Asthma
    • ADRENALINE 1 IN 10,000 INDICATIONS?
      Cardiac arrest
      Post ROSC cardiac support
    • ASPIRIN is classed as an analgesic drug.
    • ASPIRIN INDICAIONS?
      ECG evidence suggestive of an MI or ischeamia
    • GTN INDICATIONS?
      Cardiac chest pain due to MI or angina if systolic BP is more than 90 mmHg
      Acute heart failure with ischaemia and uncontrolled hypertension
      Patients with a suspected cocaine overdose presenting with chest pain
    • Efficacy - the ability of a drug to produce a desired effect
    • pharmacokinetics - the study of the body interaciton with a drug
    • pharmacodynamics - the study of how a drug affects the body
    • Drug affinity - the extent to which a drug binds to receptors at any given drug concentration or the firmness with which the drug binds to the receptor
    • Receptor - A specialised target macromolecule that binds a drug and mediates its pharmalogical action
    • Antagonist - A substance that stops the action of effect of another substance
    • chronotope - a drug that effects heart rate
    • agonist - a drug that binds to a receptor inside a cell or on its surface and causes the same action as the substance that usually binds
    • Partial agonist - binds to an active receptor, but are not able to elicit maximum possible response
    • adrenoreceptors - mediate the central and peripheral actions of the neurotransmitters adrenaline and noradrenaline
    • cholinoceptors - receptors which respond to the transmitter acetylcholine and are mostly parasympathetic
    • half-life - the time it takes for the amount og drugs active substance in your body to reduce by half
    • first pass metabolism - medication undergoes metabolism at a specific location in the body. this decreases the active drugs concentration upon reentering systemic circulation
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