Budesonide

• What is budesonide?

  ICS
• What are the indications of budesonide?

  Asthma
• What are the side effects of budesonide?

  Headache

  Oral thrush

  Voice alteration
• What is the pharmacology of budesonide?

  Target: Glucocorticoid receptor

  Action: Agonist
• MOA - budesonide

  Bind to glucocorticoid receptor -> mediates changes in gene expression Transrepression -> decreased pro-inflammatory mediators Transactivation -> increased anti-inflammatory mediators