The nucleus has a defined structure and internal organisation. The nucleus is surrounded by a double membrane (the nuclear envelope); hence, it has an inner and outer membrane with a perinuclear space. The nucleus contains chromatin, has a meshwork of intermediate filaments that form the nucleoskeleton and contains a nucleolus. The nucleus does not contain Golgi, Lysosomes, or Mitochondria, and it does not have a single membrane.
Which of the following are carried out in the nucleus?
Gene transcription
Gene translation
Protein production
Ribosome assembly
cDNA production
mRNA production
mRNA splicing
rRNA cleavage
rRNA production
tRNA production
1, 4, 6, 7, 8, 9, 10
mRNA,rRNA and tRNA are all produced in the nucleus by gene transcription. The splicing of mRNA, to remove introns, occurs in the nucleus, as does the cleavage of rRNA to make the different rRNA molecules. Finally, ribosomal proteins are imported into the nucleus, so the small and large subunits of the ribosomes can be formed. Genes are not translated, cDNA is not produced (cDNA is produced by the reverse transcription of mRNA) and proteins are not produced (this occurs in the cytosol).
Which of the following are true?
No transport is allowed through the pore
The nuclear pore consists of one protein molecule
The nuclear pore contains several hundred protein subunits
The nuclear pore contains several thousand protein subunits
The nucleus has a few hundred pores
The nucleus has around 50 pores
The nucleus has one pore
The nucleus has several thousand pores
The nucleus has tens of thousands of pores
Transport through the nuclear pore can occur in both directions
Transport through the nuclear pore is gated
Transport through the nuclear pore is not gated
3, 8, 10, 11
Which of the following are true?
Large molecules (> 60 kDa) can diffuse rapidly through the nuclear pore
Large molecules (> 60 kDa) move slowly through the pore
Large molecules (> 60 kDa) need import and export signals
Molecules between 5 - 60 kDa can diffuse rapidly through the nuclear pore
Molecules between 5 - 60 kDa move slowly through the pore
Molecules between 5 - 60 kDa need import and export signals
Small molecules (< 5 kDa) can diffuse rapidly through the nuclear pore
Small molecules (< 5 kDa) move slowly through the pore
3, 5, 7
Which of the following are true for rRNA?
Cells contain around hundred copies of the gene encoding rRNA
Cells contain around ten copies of the gene encoding rRNA
Cells contain multiple copies, around 200, of the gene encoding rRNA
Cells contain only one copy of the gene encoding rRNA
rRNA is produced from cDNA
rRNA is produced from mRNA
rRNA is produced from rDNA
rRNA is produced from tRNA
rRNA makes up a large amount, up to 80%, of the total RNA in a cell
rRNA makes up a small amount, up to 8%, of the total RNA in a cell